An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity

نویسندگان

  • Yu-Ren Liao
  • Ping-Chung Kuo
  • Jun-Weil Liang
  • Yuh-Chiang Shen
  • Tian-Shung Wu
چکیده

A naturally occurring enynyl-benzenoid, benzocamphorin F (1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by comprehensive spectral analysis. It displays anti-inflammatory bioactivity and is valuable for further biological studies. The present study is the first total synthesis of benzocamphorin F and the developed strategy described is a more efficient procedure that allowe the large-scale production of benzocamphorin F for further research of the biological activity both in vitro and in vivo.

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عنوان ژورنال:

دوره 13  شماره 

صفحات  -

تاریخ انتشار 2012